Maria João Gama Selected Research

ursodoxicoltaurine

1/2019	Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy.
12/2018	Tauroursodeoxycholic Acid Improves Motor Symptoms in a Mouse Model of Parkinson's Disease.
10/2017	Tauroursodeoxycholic Acid Protects Against Mitochondrial Dysfunction and Cell Death via Mitophagy in Human Neuroblastoma Cells.
10/2017	Erratum to: Tauroursodeoxycholic Acid Protects Against Mitochondrial Dysfunction and Cell Death via Mitophagy in Human Neuroblastoma Cells.
1/2017	Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease.
1/2017	Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease.

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Maria João Gama Research Topics

Disease

6	Neuroblastoma 10/2017 - 02/2009
5	Parkinson Disease (Parkinson's Disease) 12/2018 - 06/2009
4	Mitochondrial Diseases (Mitochondrial Disease) 12/2018 - 01/2017
3	Neuroinflammatory Diseases 07/2021 - 12/2018
3	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2017 - 01/2013
1	Multiple Myeloma 03/2022
1	Neoplasms (Cancer) 03/2022
1	Hematologic Neoplasms (Hematological Malignancy) 03/2022
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 03/2022
1	Parkinsonian Disorders (Parkinsonism) 12/2018
1	Tremor (Tremors) 12/2018
1	Alzheimer Disease (Alzheimer's Disease) 01/2010
1	Huntington Disease (Huntington's Disease) 07/2008

Drug/Important Bio-Agent (IBA)

6	ursodoxicoltaurineIBA 01/2019 - 01/2017
5	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 07/2021 - 06/2009
4	Cholesterol 24-Hydroxylase (CYP46A1)IBA 01/2016 - 01/2010
2	AntioxidantsIBA 01/2019 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 06/2009
2	Proteins (Proteins, Gene)FDA Link 04/2013 - 02/2009
2	theasinensin AIBA 01/2013 - 09/2012
2	CholesterolIBA 01/2013 - 07/2008
1	Proteasome InhibitorsIBA 03/2022
1	EnzymesIBA 01/2019
1	Adenosine Triphosphate (ATP)IBA 12/2018
1	Oxidoreductases (Dehydrogenase)IBA 01/2015
1	trichostatin A (A 300)IBA 01/2013
1	Histone Deacetylase InhibitorsIBA 01/2013
1	Phosphotransferases (Kinase)IBA 09/2012
1	Histones (Histone)IBA 09/2012
1	Okadaic AcidIBA 09/2012
1	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 09/2012
1	MitogensIBA 09/2012
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 09/2012
1	Glutathione S-Transferase piIBA 02/2009

Therapy/Procedure

1	Therapeutics 03/2022